Hopaju Inc

  Stoneman Syndrome: When the Body Turns to Stone Imagine your muscles and tendons slowly turning into bone — trapping you inside your own body. This is the heartbreaking reality faced by people with Stoneman Syndrome , medically known as Fibrodysplasia Ossificans Progressiva (FOP) . At Hopajuinc , we believe in raising awareness about such rare conditions — not to create fear, but to inspire gratitude, empathy, and the will to support those living with them. What Is Stoneman Syndrome (FOP)? Stoneman Syndrome causes the body’s soft tissues to slowly transform into bone Fibrodysplasia Ossificans Progressiva is an ultra-rare genetic disorder that causes the body’s connective tissues — such as muscles, ligaments, and tendons — to gradually transform into bone . Over time, joints become locked in place , leading to severe, irreversible disability. Even small injuries can trigger bone formation where it shouldn’t exist. Only about 1 in 2 million people worldwide live with thi...

  Congenital Leptin Deficiency: Understanding This Rare Genetic Disorder and Its Impact on Childhood Obesity Introduction Imagine feeling hungry all the time, no matter how much you eat. For most people, this sounds unimaginable — but for individuals born with Congenital Leptin Deficiency (CLD) , it’s an everyday reality. This rare genetic disorder prevents the body from producing leptin , a hormone that signals the brain when we’ve had enough to eat. Without it, hunger never stops, leading to extreme overeating and rapid weight gain from early childhood. In this blog, we’ll explore the causes, symptoms, diagnosis, and treatments of this rare condition, and how awareness and early medical support can transform lives. What Is Leptin and Why Is It Important? Leptin sends signals to the brain to control appetite and body weight Leptin is a hormone produced by fat cells (adipose tissue) that plays a critical role in regulating hunger and metabolism . When we eat, leptin s...