Hopaju Inc

  Congenital Leptin Deficiency: Understanding This Rare Genetic Disorder and Its Impact on Childhood Obesity Introduction Imagine feeling hungry all the time, no matter how much you eat. For most people, this sounds unimaginable — but for individuals born with Congenital Leptin Deficiency (CLD) , it’s an everyday reality. This rare genetic disorder prevents the body from producing leptin , a hormone that signals the brain when we’ve had enough to eat. Without it, hunger never stops, leading to extreme overeating and rapid weight gain from early childhood. In this blog, we’ll explore the causes, symptoms, diagnosis, and treatments of this rare condition, and how awareness and early medical support can transform lives. What Is Leptin and Why Is It Important? Leptin sends signals to the brain to control appetite and body weight Leptin is a hormone produced by fat cells (adipose tissue) that plays a critical role in regulating hunger and metabolism . When we eat, leptin s...